Advanced Electron Spin Resonance

The Centre for Advanced Electron Spin Resonance (CAESR) provides a state-of-the-art facility for ESR spectroscopy analysis across a range disciplines including biological systems.

The ability to selectively label any given region of a system makes Advanced Electron Spin Resonance the technique of choice for the study of large biological systems.

Areas of application include:

  • Pathogen-Host interactions in enteroviral systems
  • Protein-protein recognition (e.g. during electron transfer in P450 catalysis)
  • The study of molecular wires
  • Conformational changes during enzyme catalysis
  • Assemblies of large biological structures e.g. proteins , viruses
  • MRI contrast reagents and their derivatives

The Advanced Electron Spin Resonance facilities are housed in the Inorganic Chemistry building at the Department of Chemistry and provide opportunities for Organic Chemistry, Inorganic Chemistry, Pathology, Chemical Biology, Physics, and Quantum computing.

CAESR facilities can be accessed on an independent, collaborative or commercial service basis. Interested parties wishing to access these facilities or discuss how ESR might be applied to their own areas of activity are encouraged to make contact to discuss their needs and the experienced researchers who manage the facility will assess each project on a case-by-case basis.

Available resources:

  • EPR User Spectrometers
  • EMXmicro: X-band CW
  • E580: X-/Q-band CW/pulsed, Arbitrary Waveform Generator
  • E680: X-/W-band CW/Pulsed

Development Spectrometers

  • EMX: X-band, older style
  • E380: X-band pulsed/CW
  • HF EPR Instruments, Inc., 130 GHz: D-band pulsed/CW

Resonators

  • X-Band CW Resonators
  • X-band CW/Pulse Resonators
  • Q-band CW/Pulsed Resonator
  • W-band CW/Pulsed ENDOR Resonator

Photo-excitation Sources

  • 410-2200nm OPO Laser, 20 Hz
  • 355, 532, 1064 nm Nd:YAG, 10Hz
  • 300W Xenon Arc lamp

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