Health Innovation Challenge Fund: Informatics to assist Clinical Decision Making

Requirement to preserve and analyse the huge datasets generated by various clinical tools. Proposals must harness the potential of this complex data and make it clinically accessible and useful information for clinicians, and must seamlessly integrate with current hardware and software infrastructures.

Health Innovation Challenge Fund: Informatics to assist Clinical Decision Making

Key points/focus:

Solutions could involve one or more of the following:

  • analysis of patterns in accumulated historical data and in newly acquired data to identify changes in a patient's condition in real time or provide early warning of any deterioration
  • use of data fusion techniques to produce 'smart' alerts for patients in high-dependency areas who are monitored using static, wired or wireless physiological monitoring
  • creation of algorithms to extract and interpret clinically relevant information from complex datasets
  • development of innovative methods to link together different types of data to aid or guide clinical decision making
Specifically out of scope for this call are:
  • bioinformatics and software for analysis and interpretation of genome data
  • patient record management or patient administration systems
  • clinic or practice management systems
  • clinical trial management software

Other comments:

All proposals must meet the Essential Requirements of the HICF scheme and address at least one of its specific themes, addressing either a single theme within the current call or spanning several themes. Project teams must contain strong clinical representation and will preferably be clinically led. Projects must advance to first testing in man within the duration of the HICF project and have the potential to benefit patients within the following 3-5 years having demonstrated efficacy and received regulatory approvals. Projects must have already demonstrated ‘proof-of-principle’ supported by experimental and, where feasible, in vivo data. Projects must include a plan to progress the technology or intervention to the stage at which it is sufficiently validated, de-risked or developed to be attractive to commercial organisations, not-for-profit organisations and/or healthcare providers. Proposals must include a commercial strategy that takes into account the regulatory pathway, IP management, commercial barriers, health economics and routes to market. The HICF will not fund:

  • early stage/ basic research
  • clinical trials
  • health delivery research by the NHS
  • delivery or provision of health services by or within the NHS
  • projects that could secure funding from industry or venture capital
  • drug development
  • regenerative medicine or vaccine development programs

Applications Procedure:

Forms and guidance notes can be found on the Wellcome Trust website.