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Closed-loop deep brain stimulation to influence sleep state

Image from Licence Details: Closed-loop deep brain stimulation to influence sleep state

Applications: Neuromodulation, Neurostimulation, Deep-brain stimulation, Sleep disorder.

Features  Benefits
  • Allows transitioning to lighter or deeper sleep through deep-brain stimulation.
  • Potential to be used to treat excessive daytime sleepiness (e.g. narcolepsy), and pathological sleep caused by neurological disorders.
  • Avoids pharmacological agents to address sleep disorders, which may impact the action of other drugs and induce tolerance.
  • Provides treatment options to under-served patients such as young people who have recovered from traumatic brain injury, where no drug treatment currently exists.
  • Personalised, adjustable pulses delivered according to patient-specific sleep features and recorded physiological signals (e.g. from wearables), or according to a desired rhythm.
  • Adaptable to the patients’ real-time needs and in sync with circadian rhythms.
  • Software/stimulation patterns can be incorporated into pre-implanted devices such as those targeting Parkinson’s disease, tremor or psychiatric disease.
  • Avoids further invasive and costly procedures.
  • Improves the patients existing therapy by alleviating sleep-related symptoms.
  • Can enhance plasticity mechanisms.
  • Ability to modulate areas of the brain relevant to learning and memory.

Available for:

  • Licensing
  • Co-development
  • Consulting
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