A scalable mRNA synthesis platform for manufacturing mRNAs with batch consistency and high translational output

A scalable mRNA synthesis platform for manufacturing mRNAs with batch consistency and high translational output.

Applications: Synthesis of next generation mRNA therapeutics: vaccine development, cancer therapeutics, rare genetic disorder therapeutics, personalised medicine

Features Benefits
mRNA template plasmid platform with a novel template encoded poly(A) design Improved plasmid stability in bacterial host during propagation and subcloning
Flexible poly(A) tail length design Streamlines quality control process
Proprietary 5’ and 3’ UTR sequences in combination with signal peptide sequences Streamlines regulatory compliance
Highly modular plasmid design Production of synthesis mRNAs with poly(A) tails up to ~200 nucleotides in length
Maximising translational output
Streamlines regulatory compliance
High translational output of intracellular or secreted proteins
Enables streamlined, speedy, and cost-effective manufacturing of novel/personalised mRNAs drugs

Awaiting patent and Available For

  • Co-development
  • Consulting
  • Licensing

Project Number: 22207, 22849

Industry Categories

Life Sciences