The beads have anti-fouling properties that make them particularly suitable for binding and purification of low concentration molecules from complex mixtures.
Features
Benefits
Zwitterionic polymer grown on surface of bead
Improves coverage and antifouling properties compared to attached polymers, so very low levels of interfering biological molecules
Polymer generated using reversible addition fragmentation chain transfer (RAFT)
Can be used for a broader range of monomers than other processes, including ATRP
Conjugating ligands attached to activated surface
Can attach antibodies, organic compounds, metals, proteins or hydrophobic molecules
Highly sensitive
Determination of pg/ml levels of specific protein from populations in the mixture
Can purify low levels of exosomes and demonstrated on neuronal exosomes from blood