Vaccine delivery technology for greater compliance and coverage, and cost effective vaccination campaigns
Novel injectable microcapsules, produced by high throughput microfluidics, enabling complete vaccination via a single injection. After injection, the microcapsule shell degrades, providing a burst release of Active Pharmaceutical Ingredients (APIs) at a pre-programmed timepoint.
Applications: vaccination, drug delivery
| Features | Benefits |
|---|---|
| Each microcapsule (<80μm) has a distinct aqueous liquid core in which a range of APIs can be dissolved, surrounded by a shell that degrades after a tuneable time delay | Programmable burst release of the API(s) |
| Microfluidic system that allows precise control over microcapsule architecture at micrometre scale and scalable, continuous processing | Allows multiple therapies to be administered through standard clinical needles in a single injection |
| Allows “one shot” vaccination (prime + booster in a single injection), improving immunisation campaigns by simplifying logistics and improving coverage | |
| Excellent microcapsule uniformity and batch-to-batch reproducibility | |
| Chip design allows for high throughput production and easy scaling through parallelisation | |
| Real-time control over microcapsule core size and shell thickness | |
| Easy postproduction quality control of the loading and particles | |
| API protected from exposure to harsh conditions that can damage its structure or affect its function |