Next-generation HIV immunotherapy: TCR technology

Image from Licence Details: Next-generation HIV immunotherapy: TCR technology

Applications: T cell receptor (TCR) therapy, Engineered T cells, HLA-E restricted immunity, HIV-1 treatment

Our breakthrough technology harnesses the body’s immune power to fight HIV at its source.

 

Features Benefits
  • Smart HIV Targeting
  • Our T-cell receptors (TCRs) are designed to recognise hidden HIV fragments presented by a unique immune molecule (HLA-E). This helps overcome HIV’s ability to hide and mutate, offering broader protection across patients.
  • Precision-Engineered Receptors
  • Each TCR is built from well-defined genetic sequences, ensuring consistent quality, predictable performance, and easier regulatory approval.
  • Gene-Based Delivery
  • We use advanced DNA or RNA vectors to insert these TCRs into immune cells. This allows efficient, scalable manufacturing of patient-ready cell therapies.
  • Engineered Immune Cells
  • T cells equipped with our TCRs can seek out and destroy HIV-infected cells—potentially leading to long-term viral control or even functional cure.
  • Transformative HIV Treatment Potential
  • Designed to work alongside or beyond antiretroviral therapy (ART), this approach could redefine how HIV is managed and move us closer to ending the epidemic.

Patent pending and available for:

  • Licensing
  • Co-development
  • Consulting

 

Request more information
about this technology

Back to Technologies Available

Sparks Background Image

Ready to get in touch?

Contact Us
Sparks Background Image
© Oxford University Innovation