A new strain of gonococcus, produced by replacing the native PorB with analogs from another bacterium to enhance immunogenicity, as new generation outer membrane vesicle (OMV) vaccine.
Features
Benefits
Simple replacement of Neisseria gonorrhaeae porB gene with Neisseria Meningitidis porB gene
Enhances immunogenicity whilst maintains viability of Neisseria gonorrhoeae
§Deletion of RmpM gene
Increases OMV production which is a key component of OMV vaccines