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A scalable mRNA synthesis platform for manufacturing mRNAs with batch consistency and high translational output

Image from Licence Details: A scalable mRNA synthesis platform for manufacturing mRNAs with batch consistency and high translational output

Applications: Synthesis of next generation mRNA therapeutics: vaccine development, cancer therapeutics, rare genetic disorder therapeutics, personalised medicine

Features Benefits
  • mRNA template plasmid platform with a novel template encoded poly(A) design
  • Improved plasmid stability in bacterial host during propagation and subcloning
  • Streamlines quality control process
  • Streamlines regulatory compliance
  • Flexible poly(A) tail length design
  • Production of synthesis mRNAs with poly(A) tails up to ~200 nucleotides in length
  • Maximising translational output
  • Streamlines regulatory compliance
  • Proprietary 5’ and 3’ UTR sequences in combination with signal peptide sequences
  • High translational output of intracellular or secreted proteins
  • Highly modular plasmid design
  • Enables streamlined, speedy, and cost-effective manufacturing of novel/personalised mRNAs drugs

Patent filed and available for

  • New venture creation
  • Co-development
  • Licensing
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