Vaccine delivery technology for greater compliance and coverage, and cost effective vaccination campaigns

Image from Licence Details: Vaccine delivery technology for greater compliance and coverage, and cost effective vaccination campaigns

Applications: vaccination, drug delivery

Novel injectable microcapsules, produced by high throughput microfluidics, enabling complete vaccination via a single injection. After injection, the microcapsule shell degrades, providing a burst release of Active Pharmaceutical Ingredients (APIs) at a pre-programmed timepoint.

Features Benefits
  • Each microcapsule (<80μm) has a distinct aqueous liquid core in which a range of APIs can be dissolved, surrounded by a shell that degrades after a tuneable time delay.
  • Programmable burst release of the API(s)
  • Allows multiple therapies to be administered through standard clinical needles in a single injection.
  • Allows “one shot” vaccination (prime + booster in a single injection), improving immunisation campaigns by simplifying logistics and improving coverage.
  • Microfluidic system that allows precise control over microcapsule architecture at micrometre scale and scalable, continuous processing.
  • Excellent microcapsule uniformity and batch-to-batch reproducibility.
  • Chip design allows for high throughput production and easy scaling through parallelisation.
  • Real-time control over microcapsule core size and shell thickness.
  • Easy postproduction quality control of the loading and particles.
  • API protected from exposure to harsh conditions that can damage its structure or affect its function.
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