The DHP-3D and DHP-5D Programmes

The DHP-3D and DHP-5D are preference-based measures that can be used to generate utility values to produce quality-adjusted life years (QALYs).

How are you demonstrating the value of your diabetes intervention in your HEOR activities?

The DHP-3D and 5D are data analysis tools for extracting valuable health economic data from health outcome measures data in diabetes. Using data collated from responses to the widely regarded Diabetes Health Profile (for the DHP-3D) along with the SF-36 (for the DHP-5D), health economists can now build Quality-Adjusted Life Year (QALY) evidence in support of their interventions.

 

Patient reported outcomes for diabetes patients

The Diabetes Health Profile-18 (DHP-18) is a Patient Reported Outcome (PRO) measure that provides a detailed assessment of emotional and behavioural health of people with diabetes. However, whilst scores generated directly using the DHP-18 provide an excellent means for judging the effectiveness of health care interventions, they have only a limited application in economic evaluation because they are not based on preferences. The DHP-3D and DHP-5D enable data collected using the DHP-18 to be used in economic evaluation by estimating a preference-based single index measure for health using general population values. The DHP-3D and DHP-5D were developed by a team at The University of Sheffield.

What are the DHP-3D and DHP-5D?

The DHP-3D and DHP-5D are diabetes-specific preference-based measures, that consist of:-

1) a descriptive system that is used to assign each respondent to a health state for each time point; and

2) utility scoring weights that have been generated using preferences of the UK general population.

The DHP-3D has 3 dimensions:

1) Mood/ psychological distress
2) Eating
3) Social limitations/ barriers to activity

Whereas the DHP-5D has 5 dimensions:

1) Mood
2) Eating
3) Social Limitations
4) Hypoglycaemic attacks
5) Vitality

The generated utility weights are then embedded into short programme files to be used with common data analysis packages SPSS or STATA.

 

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How do the DHP-3D and DHP-5D generate preference scores?

The DHP-3D and DHP-5D come with a set of preference weights obtained from a sample of the general population (in the United Kingdom) using the recognised valuation technique of time trade-off. Members of the general population were asked to value a selection of health states from which a model has been estimated to predict all the health states described by the DHP-3D and by the DHP-5D.

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How do I use the DHP-3D and DHP-5D programmes?

The DHP-3D and 5D are generated by using either an SPSS syntax file or a Stata do file on your acquired data. The files therefore come as 4 different options

For use with IBM SPSS™ software platform:

1)     DHP-3D_programme_SPSS.sps

2)     DHP-5D_programme_SPSS.sps

and for use with STATA software:

3)     DHP-3D_programme.do

4)     DHP-5D_programme.do

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What is the difference between DHP-3D and DHP-5D?

The DHP-3D has 3 dimensions of mood, eating and social limitations, and is generated using DHP-18 data only. The DHP-5D has 2 additional dimensions of hypoglycaemic attacks and vitality, but requires additional data to the DHP-18.

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What data do I need to collect to produce the DHP-3D utility scores?

The DHP-3D requires DHP-18 only.

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What data do I need to collect to produce the DHP-5D utility scores?

The DHP-5D requires additional data from:

–        DHP-1 (Item 11, “Worry about doing too much and going hypo?”)

and

  • The SF-36v2 (Item 9i, “Did you feel tired?”)

 

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Further important information for users

Please note the following important information

1) A licence to use the DHP-5D programme files does not give any rights to use the SF-36 health survey and if users wish to use the SF-36 Version 2 they should seek permission from the copyright owner.

2) All permissions / licences to use the Diabetes Health Profile (DHP) can be secured from the Clinical Outcomes team.

3) The weights are UK population specific and so should only be used on DHP / SF-36 results acquired from a UK population. However, if users wish to acquire weights to use in other territories then please contact the Clinical Outcomes team.

 

Got a question? Further details can be found in our FAQ’s for the DHP-3D & 5D in our useful links section.

Alternatively, please do not hesitate to get in touch with us via healthoutcomes@innovation.ox.ac.uk.

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