Gene therapy for chronic pain and epilepsy
A new approach to treat chronic pain and epilepsy based on the over expression of a modified CASPR2 polypeptide in sensory ne...
Computational antibody modelling and prediction platf...
Oxford researchers have encompassed SAbDab/SAbPred tools, for structural antibody modelling and prediction, into a virtual ma...
Further improved peptide tag technology: SpyTag and S...
An increased reaction rate of SpyTag and SpyCatcher by more than two orders of magnitude, whilst retaining all the advantageo...
INDIANA – IN-cell DIffusion ANAlysis
An in-cell NMR diffusion method to characterise the size, abundance and permeability of cells.
AFIRM: Amyloid Formation and Inhibition Mechanism
Software for the determination of amyloid formation mechanism and how this is inhibited by the addition of drugs, using nucle...
Mic-seq: single cells provirus monitoring to inform o...
A novel method to isolate, characterise, and quantify rare population cells that comprise the HIV reservoir.
Neuromorphic technology based on new physics
A signal processing platform that takes on the characteristics of a neuron without suffering from the power dissipation probl...
Bespoke reference electrode for electrochemical senso...
A novel solid-state electrolyte-free reference electrode suitable for miniaturisation.
RELATE: estimating genome wide genealogies for thousa...
Software that enables genome-wide genealogies in the form of trees that adapt to changes in local ancestry caused by recombin...
Single cell isolation
A novel technique for ensuring monoclonality in a well plate for workflows that rely on single cell isolation.
HTSense: Simplifying the analysis and design of high ...
A flexible method for visualising complex datasets and designing validation studies.
Targeted drug delivery to the brain for treating neur...
Novel drug delivery vehicles capable of directly targeting areas of the brain affected by abnormal tau aggregation, in diseas...
A method for precisely tuning gene expression levels ...
Researchers at the University of Oxford have developed a method for precise, stepwise control of endogenous gene expression l...
New lead compounds for treating cancers involving Ras...
Oxford University researchers have developed small molecule inhibitors of Ras proteins, important therapeutic targets in a la...
The therapeutic potential of chemically synthesised o...
Researchers at the University of Oxford have developed a chemical synthesis strategy for producing DNA incorporating non-natu...
Hepatitis C vaccine
A viral-vectored vaccine incorporating a novel immunogen for a pan-genotypic Hepatitis C protection based on genomic segments...
Single molecule sequencing for single-molecule phenot...
A high throughput single-molecule sequencing method that links structure to function.
Synthetic Cas9-based programmable transmembrane recep...
A novel family of synthetic Cas9-based programmable transmembrane receptors that enable conditional control of gene expressio...
SnoopLigase for catalysis of ligation between two pep...
A tool that greatly enhances the functionality and diversifies the uses of the current Tag/Catcher peptide tag technology
Staphylococcus aureus vaccine
Oxford researchers have identified two S. aureus proteins with the potential to be used as components of a vaccine a...
Inducible CRISPR-TR system for the conditional regula...
Oxford researchers have developed an inducible CRISPR-based transcription regulator system that allows for spatiotemporal con...
Stratification method for proximal colorectal cancer ...
Oxford researchers have developed a method for stratifying colorectal cancer patients based on the location and biomarker pro...
A method for single restriction enzyme-based scarless...
Oxford University academics have developed a method for hierarchical assembly of DNA fragments up to 200kb using a single res...
New class of molecular adjuvant
Oxford researchers have identified a family of enzymes that can increase immunogenicity towards a wide range of fused antigen...
Dynamic Consent
Oxford researchers have developed a personalised, web-based interface for the advanced management of fully informed consent. ...
Semantic image segmentation
Oxford researchers have developed a novel neural network component for semantic image segmentation, with diverse and numerous...
Multivalent Dengue Vaccine
A universal Dengue vaccine to induce cellular immune responses against all dengue virus serotypes
Brain tumour detection and treatment
Low dose cytokines temporarily increase the permeability of the blood-brain barrier, improving the delivery of agents to dete...
Stem cell immunotherapy
Cross-presenting dendritic cells derived from a patient's own skin cells promise to be the ideal starting point for the devel...
Efficient cofactor regeneration
A biocatalysis system that has the potential to reduce the manufacturing costs for the pharmaceutical and fine chemicals indu...
Adenovirus: vector improvements
Modified promoter sequence which significantly enhances protein expression levels compared to standard adenovirus vectors....
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