Method for creating a nitric oxide generating coating for medical devices
A method for generating therapeutic gas, nitric oxide (NO), from a coating of amine-functionalised graphene that can be used for medical devices, such as stents.
Applications: Medical devices for cardiovascular disease, Cerebrovascular disease, Eye diseases and aneurysms
| Features | Benefits |
|---|---|
| Novel amine-functionalised graphene oxide material that generates NO, negating external NO sources | Allows commercially viable in-vivo NO generating medical devices to be engineered |
| Method provides a stable and strong coating that can be added to medical devices, and the coating thickness can be easily varied | Maintains structural integrity and is non-toxic; Coating biodegradable medical devices has minimal effect on their degradation |
| The coating generates therapeutic levels of NO in a sustained, controlled and slow manner at the site of need in the body, with trials ongoing | Reduces the risk of medical complications after implantation of a medical device such as restenosis, bacterial infection and biofilm formation |
| Straightforward and simple application of the coating using a dip coating method | Can easily apply a smooth and uniform coating to complex 3D geometries and form factors; Cost-effective functionalisation approach; Scalable method of manufacturing medical devices |
Patented and Available For
- Co-development
- Consulting
- Licensing