Method for diagnosis of Early Onset Pre-eclampsia (EOPE)

Applications: Diagnostics, women’s health

Preeclampsia is a major cause of maternal and perinatal morbidity and mortality worldwide. Identifying women with high risk of developing preeclampsia in early pregnancy remains challenging. Researchers at Oxford have developed a method to identify those at risk of developing the condition that offers advantages over existing diagnostic approaches. (Jiang, S. et.al. Hypertension, 2023)

Features	Benefits
Detects patients who will develop EOPE in the first trimester.	Allows for early monitoring and intervention leading to better patient outcomes.
Based on analysis of biomarkers found on circulating placental-derived small extra-cellular vesicles (psEV).	Simple sample collection and preparation.
Requires only a small quantity (12.5ug) of blood serum.	Can be run alongside routine maternal screening.

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Method for diagnosis of Early Onset Pre-eclampsia (EOPE)

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