Delivering closed-loop deep brain stimulation using multiple electrodes

Applications: Closed loop neuromodulation systems.

Current closed loop DBS systems fail to address how applying stimulation to multiple regions can affect treatment. This invention has the potential to enable delivery of closed loop DBS which accounts for activity in multiple brain regions.

Features	Benefits
Utilises signals extracted from multiple brain regions in a closed-loop DBS strategy	Provides a better understanding of the physiological state of a patient and enables the construction of more accurate feedback signals which better correlate with their symptoms
Uses multiple stimulating electrodes to deliver closed-loop DBS	Allows multiple brain regions to be better targeted, potentially leading to more effective treatment with less energy usage and fewer side effects
Can predict whether multi-contact/multi-electrode stimulation is likely to be effective for a given patient	Ensures that our closed-loop system is only used as a treatment option for patients who are most likely to benefit from it
Using well-established models of neural circuits, we have demonstrated our system to be more effective at desynchronising pathological activity than existing closed-loop DBS methods	May provide more effective treatment for patients with certain neurological disorders and solves the complexity problem of tuning multi-electrode DBS systems

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Delivering closed-loop deep brain stimulation using multiple electrodes

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